Heart failure & cardiomyopathiesCohort study

Outcomes of Heart Transplant Donation After Circulatory Death

J Am Coll CardiolPublished

  • Retrospective cohort study
  • single-centre
  • observational

Authors' conclusion

In the largest single-center comparison of DCD and DBD heart transplantations to date, outcomes among DCD recipients are noninferior to those of DBD recipients.

Study context

Population
Adults undergoing heart-only transplantation, single centre, January 2020 to January 2023
Participants
385 adults
Exposure
DCD vs DBD heart transplantation
  • DCDn = 122

Main finding

As reported in the abstract

1-year survival, severe primary graft dysfunction, treated rejection in first year, cardiac allograft vasculopathy at 1 year · 1 year
  • No significant differences between DCD and DBD in 1-year survival, severe primary graft dysfunction, treated rejection during the first year or cardiac allograft vasculopathy at 1 year

Observational data: associations, not effects.

Original publication

Outcomes of Heart Transplant Donation After Circulatory Death. J Am Coll Cardiol. Published 10 October 2023. doi:10.1016/j.jacc.2023.08.006

Summarised from the published abstract; every number is checked against it