Heart failure & cardiomyopathies
Long-Term Outcomes From a Decade of Donation After Circulatory Death Heart Transplantation in Australia
Main finding · SurvivalResult — go to the resultHazard ratio 0.9 95% CI 0.5–1.4Authors' conclusion
Heart transplant recipients from DCD donors have similar survival and freedom from CAV at 10 years post HT when compared with a contemporary cohort of recipients from DBD donors.
Study context
- Population
- Consecutive heart transplant recipients, St Vincent's Hospital Sydney, July 2014 to December 2024
- Participants
- 118 vs 385
- Exposure
- DCD vs DBD heart transplantation
- DCDn = 118
- DBDn = 385reference
- Outcome
- Patient survival and freedom from CAV
- Follow-up
- 10 years
Methodological detailssingle-centre, consecutive recipients
- Single-centre
- Consecutive recipients
Main finding
Survival
Hazard ratio
0.9
95% CI 0.5–1.4
P = 0.5
By group
DCD
- 10-year survival
- 67%
- 10-year freedom from cardiac allograft vasculopathy (CAV)
- 61%
DBD
- 10-year survival
- 64%
- 10-year freedom from CAV
- 41%
10-year survival
DCD67%
DBD64%
10-year freedom from cardiac allograft vasculopathy (CAV)
DCD61%
DBD41%
DCD vs DBD
HR 0.9 (95% CI 0.5–1.4); P = 0.5
As reported in the abstract
Observational data: associations, not effects.
Further findings
1-year survival
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Asystolic warm ischemic time as risk factor for severe primary graft dysfunction in DCD HT · only retrieval-specific independent risk factor | 1.4 (1.1–2.0) | P = 0.03 | |
| 0.512Odds ratio (log scale) |
1-year survival
- No significant difference in short-term survival
Safety
Severe primary graft dysfunction
Severe primary graft dysfunction
- No significant difference
Original publication
Long-Term Outcomes From a Decade of Donation After Circulatory Death Heart Transplantation in Australia. JACC Heart Fail. Published 10 June 2026. doi:10.
Summarised from the published abstract; every number is checked against it