Valvular & structural heart disease
Outcomes of Patent Foramen Ovale Transcatheter Closure: Should a Short Aortic Rim Preclude Closure?
Authors' conclusion
In a large cohort with long-term administrative follow-up (1,394 patient-years), implantation of an Amplatzer PFO device was performed safely even in patients with a short aortic rim.
Study context
- Population
- Patients undergoing patent foramen ovale (PFO) closure with the Amplatzer PFO device for any indication, 2006–201761% short aortic rim
- Participants
- 324 patients
- Exposure
- Short vs longer aortic rim
- Outcome
- Device erosion or embolization requiring cardiac surgery
- Follow-up
- Median 7 years
Methodological detailssingle-centre, quaternary centre
- Single-centre
- Quaternary centre
Main finding
As reported in the abstract
median 7 years
- No cases of device erosion or embolization requiring cardiac surgery
- 1,394 patient-years
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Baseline characteristics by aortic rimLonger aortic rim vs Short aortic rim · diabetes 15% vs 6.5% | P = 0.04 |
| Baseline characteristics by aortic rimLonger aortic rim vs Short aortic rim · HF 15.7% vs 4% | P < 0.001 |
- Baseline characteristics by aortic rim: Most common indication cryptogenic stroke (72%)
Baseline characteristics by aortic rim
- Longer aortic rim more likely to have a non-stroke indication for closure
Original publication
Outcomes of Patent Foramen Ovale Transcatheter Closure: Should a Short Aortic Rim Preclude Closure? JACC Adv. Published 22 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →