Arrhythmias & electrophysiology

Outcomes of ventricular tachycardia ablation facilitated by pre-procedural cardiac imaging-derived scar characterization: a prospective multi-centre international registry

EuropacePublished Prospective multicentre registry

Authors' conclusion

In a large multi-centre prospective cohort, VT ablation facilitated by pre-procedural imaging is associated with favourable long-term outcomes.

Study context

Population
Consecutive patients referred for scar-related left-sided ventricular tachycardia (VT) ablation (71% ischaemic cardiomyopathy)
Participants
171 patients
Exposure
Image-guided vs image-aided VT ablation
Outcome
Overall survival and VT recurrence-free survival
Follow-up
Mean 18 ± 19 months
Methodological detailsinternational, 5 European tertiary hospitals, consecutive patients
  • International
  • 5 European tertiary hospitals
  • Consecutive patients

Main finding

As reported in the abstract

mean follow-up 18 ± 19 months

Overall survival

91%

VT recurrence-free survival

74.4%

Observational data: associations, not effects.

Further findings

Long-term ablation outcomes by cardiomyopathy type and imaging modality

No significant difference by type of cardiomyopathy
P = 0.88
No significant difference by pre-procedural imaging modality
P = 0.33

Image-guided approach

Image-guided approach feasible, safe and faster, with reduced procedure, radiofrequency and fluoroscopy times, without compromising efficacy

Imaging integrated

Cardiac magnetic resonance (CMR) integrated
159 (93%)
Multi-detector computed tomography (MDCT) integrated
113 (66%)
Both
101 (59%)

Safety

Procedure-related complications
9 (5%)

Original publication

Outcomes of ventricular tachycardia ablation facilitated by pre-procedural cardiac imaging-derived scar characterization: a prospective multi-centre international registry. Europace. Published 14 March 2025. doi:10.1093/europace/euaf051

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