Heart failure & cardiomyopathies
Outcomes with T-Wave Discordance of Left Bundle Branch Block and Preserved or Mildly Reduced Ejection Fraction
Main finding · CV death or HF hospitalizationResult — go to the resultHazard ratio 1.63 95% CI 1.011–2.628Authors' conclusion
In patients with LBBB and EF ≥ 40%, dLBBB serves as an independent predictor of a higher risk of cardiovascular death or non-fatal heart failure hospitalization.
Study context
- Population
- Patients with complete left bundle branch block (LBBB) and LVEF ≥ 40%, January 2010–December 2018
- Participants
- 707 patients
- Exposure
- Discordant vs concordant T-wave LBBB
- Outcome
- CV death or hospitalization for HF
- Follow-up
- Median 3.1 years
Main finding
CV death or HF hospitalization · median 3.1 years
Hazard ratio
1.63
95% CI 1.011–2.628
P = 0.032
dLBBBvs cLBBB
HR 1.63 (95% CI 1.011–2.628); P = 0.032
As reported in the abstract
Observational data: associations, not effects.
Further findings
Other independent predictors of primary outcome
| HR (95% CI) | P value | ||
|---|---|---|---|
| Older age | 1.023 (1.001–1.046) | P = 0.023 | |
| History of HF | 2.440 (1.524–3.905) | P = 0.001 | |
| CKD | 1.917 (1.182–3.110) | P = 0.008 | |
| Larger LV end-systolic volume | 1.046 (1.017–1.075) | P = 0.002 | |
| Lower LVEF | 0.916 (0.885–0.948) | P = 0.001 | |
| 0.20.5125Hazard ratio (log scale) |
T-wave subtype transformation during follow-up
- Transformation between subtypes in up to this proportion of patients
- 23%
- Persistent or transformed discordant LBBB (dLBBB) faced increased risk of CV death or non-fatal HF hospitalization
Original publication
Outcomes with T-Wave Discordance of Left Bundle Branch Block and Preserved or Mildly Reduced Ejection Fraction. ESC Heart Fail. Published 12 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →