Valvular & structural heart disease

Pacing considerations in patients undergoing transcatheter tricuspid valve replacement: Insights from a tertiary care center

Heart RhythmPublished Patients who underwent Transcatheter Tricuspid Valve Replacement (TTVR) at Emory Healthcare

Authors' conclusion

More than 20% of patients with jailed leads after TTVR have serious complications due to lead malfunctions. TTVR-related heart block was common in our cohort (13%), and its treatment with LP or TV-sparing pacing systems was safe and effective.

Study context

Population
Patients who underwent transcatheter tricuspid valve replacement (TTVR) at Emory Healthcarepatients who underwent TTVR
Participants
73 patients
Comparison
Preexisting permanent pacing systems vs Jailed leads
  • Preexisting permanent pacing systemsn = 21
  • Jailed leadsn = 14
Outcome
Preexisting permanent pacing systems

Main finding

As reported in the abstract

Patients with preexisting permanent pacing systems

21

29%

Further findings

Management of transvenous leads at TTVR

Transvenous lead jailed
14 patients (73.7%)
Lead extraction
Five patients (26.3%)
Of those extracted: Tricuspid valve (TV)-sparing pacing system
n = 2
Of those extracted: ventricular LP
n = 2
Of those extracted: no device reimplantation
1 patient

Heart block requiring permanent pacing after TTVR

Heart block requiring permanent pacing
7 of 52 patients (13%)
Of those with heart block: received an LP
4 patients
Of those with heart block: TV-sparing pacemaker
2 patients
Of those with heart block: lead implanted across the valve
1

Follow-up

Average follow-up
10.5 months

Safety

Complications in patients with jailed leads · average follow-up of 10.5 months
21% · 3 of 14 of 14
Complications in patients with jailed leads — Fractured lead revision required
Two patients
Complications in patients with jailed leads — of the revisions: complicated by infection resulting in death
One

Complications in patients with jailed leads · average follow-up of 10.5 months

Patient with jailed right ventricular lead died suddenly 1 week after discharge

Original publication

Pacing considerations in patients undergoing transcatheter tricuspid valve replacement: Insights from a tertiary care center. Heart Rhythm. Published 24 April 2025. doi:10.1016/j.hrthm.2025.02.004

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