Cardio-oncology & other

Particulate Matter 2.5 Pollution Impact on Comorbid Cancer and Cardiovascular Disease Mortality in the U.S.

JACC AdvPublished Cross-sectional study

Authors' conclusion

Higher levels of long-term PM 2.5 exposure reported increased CVD mortality, cancer mortality and comorbid cancer and CVD disease mortality, with a pronounced detrimental effect in vulnerable and minority population.

Study context

Population
US population, county-level mortality, 2016–2020
Exposure
Counties by quartile of average daily particulate matter (PM) 2.5 density
Outcome
Age-adjusted CVD mortality, cancer mortality and comorbid cancer and CVD mortality
Methodological detailscounty-level, CDC WONDER multiple-cause-of-death database, PM 2.5 data from the 2018 CDC National Environmental Public Health Tracking system
  • County-level
  • CDC WONDER multiple-cause-of-death database
  • PM 2.5 data from the 2018 CDC National Environmental Public Health Tracking system

Main finding

As reported in the abstract

Age-adjusted mortality rates, overall

CVD age-adjusted mortality rate (range 505.0-505.7)

505.3 per 100,000 person-years

Cancer age-adjusted mortality rate (range 210.5-210.9)

210.7 per 100,000 person-years

Comorbid cancer and CVD age-adjusted mortality rate (range 61.8-62.1)

62.0 per 100,000 person-years

Observational data: associations, not effects.

Further findings

Excess mortality by Social Vulnerability Index and race (subgroups)

Disproportionate effect of PM 2.5 exposure on vulnerable and minority groups

Original publication

Particulate Matter 2.5 Pollution Impact on Comorbid Cancer and Cardiovascular Disease Mortality in the U.S. JACC Adv. Published 13 July 2024. doi:10.1016/j.jacadv.2024.101106

Composed by AI from the published abstract and checked against it. How Briefs are made →

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