Particulate Matter 2.5 Pollution Impact on Comorbid Cancer and Cardiovascular Disease Mortality in the U.S.
Authors' conclusion
Higher levels of long-term PM 2.5 exposure reported increased CVD mortality, cancer mortality and comorbid cancer and CVD disease mortality, with a pronounced detrimental effect in vulnerable and minority population.
Study context
- Population
- US population, county-level mortality, 2016–2020
- Exposure
- Counties by quartile of average daily particulate matter (PM) 2.5 density
- Outcome
- Age-adjusted CVD mortality, cancer mortality and comorbid cancer and CVD mortality
Methodological detailscounty-level, CDC WONDER multiple-cause-of-death database, PM 2.5 data from the 2018 CDC National Environmental Public Health Tracking system
- County-level
- CDC WONDER multiple-cause-of-death database
- PM 2.5 data from the 2018 CDC National Environmental Public Health Tracking system
Main finding
As reported in the abstract
Age-adjusted mortality rates, overall
CVD age-adjusted mortality rate (range 505.0-505.7)
505.3 per 100,000 person-years
Cancer age-adjusted mortality rate (range 210.5-210.9)
210.7 per 100,000 person-years
Comorbid cancer and CVD age-adjusted mortality rate (range 61.8-62.1)
62.0 per 100,000 person-years
Observational data: associations, not effects.
Further findings
Excess mortality by Social Vulnerability Index and race (subgroups)
- Disproportionate effect of PM 2.5 exposure on vulnerable and minority groups
Original publication
Particulate Matter 2.5 Pollution Impact on Comorbid Cancer and Cardiovascular Disease Mortality in the U.S. JACC Adv. Published 13 July 2024. doi:10. 1016/ j. jacadv. 2024. 101106
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