Arrhythmias & electrophysiology
Recurrences of Atrial Fibrillation Despite Durable Pulmonary Vein Isolation: The PARTY-PVI Study
Authors' conclusion
In patients with recurrent AF despite durable PVI, no ablation strategy used alone or in combination during the redo procedure appears to be superior in improving arrhythmia-free survival. Left atrial size is a significant predictor of ablation outcome in this population.
Study context
- Population
- Patients undergoing redo ablation for atrial fibrillation (AF) recurrences despite durable pulmonary vein isolation (PVI), 2010–2020
- Participants
- 219 / 168 / 101 / 56 / 7
- Exposure
- Pulmonary vein-based vs linear-based vs electrogram-based vs trigger-based ablation at redo procedure
- Linear-basedn = 219
- Electrogram-basedn = 168
- Trigger-basedn = 101
- Pulmonary vein-basedn = 56
- No additional ablationn = 7
- Outcome
- Freedom from atrial arrhythmia
Methodological details39 centres
- 39 centres
Main finding
As reported in the abstract
Arrhythmia-free survival by ablation strategy
- No significant difference in arrhythmia-free survival between ablation strategies
- Strategies used alone or in combination
Observational data: associations, not effects.
Further findings
Independent factor associated with arrhythmia-free survival: left atrial dilatation
| HR (95% CI) | P value | ||
|---|---|---|---|
| Left atrial dilatationOnly independent factor | 1.59 (1.13–2.23) | P = 0.006 | |
| 0.512Hazard ratio (log scale) |
Recurrence of atrial arrhythmia (all patients) · 12 and 24 months
- Recurrence at 12 months
- 122 (33%)
- Recurrence at 24 months
- 159 (43%)
- Follow-up 22±19 months
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Recurrences of Atrial Fibrillation Despite Durable Pulmonary Vein Isolation: The PARTY-PVI Study. Circ Arrhythm Electrophysiol. Published 20 February 2023. doi:10.
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