Pathways Linking Post-Traumatic Stress Disorder to Incident Ischemic Heart Disease in Women: Call to Action
Authors' conclusion
Traditional IHD risk factors explained a quarter of the PTSD-IHD association in women veterans, and over half of the risk of IHD associated with PTSD remained unexplained even when adjusting for a wide range of risk factors.
Study context
- Population
- US women veterans enrolled in Veterans Health Administration care, 2000–2017
- Exposure
- Post-traumatic stress disorder (PTSD) vs no PTSD
- Outcome
- Mediation of the PTSD-incident ischemic heart disease (IHD) (CAD, angina or MI) association by risk factors
Methodological detailspropensity-score matched, longitudinal
- Propensity-score matched
- Longitudinal
Main finding
As reported in the abstract
Proportion of PTSD-IHD association explained by risk factors
Traditional risk factors (hypertension, hyperlipidemia, smoking, DM)
24.2%
Psychiatric risk factors (eg, depression, anxiety, substance use disorders)
33.8%
All 13 risk factors
48.5%
Observational data: associations, not effects.
Original publication
Pathways Linking Post-Traumatic Stress Disorder to Incident Ischemic Heart Disease in Women: Call to Action. JACC Adv. Published 30 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →