Patient-Specific Registration of Segmental Jeopardy and Viability: Novel Method to Guide Revascularization in Ischemic Cardiomyopathy
Authors' conclusion
Patient-specific coronary tree-based reporting to define jeopardized but viable myocardium accurately is clinically feasible and identifies ICM patients who experience lower mortality from early revascularization.
Study context
- Population
- Patients with ischemic cardiomyopathy (ICM) (obstructive CAD and LVEF <50%) undergoing CMR and invasive coronary angiography, 2015–2022193 early revascularization
- Participants
- 941 patients
- Exposure
- Early revascularization vs no early revascularization, by jeopardized but viable myocardium
- Early revascularizationn = 193
- Outcome
- All-cause mortality
- Follow-up
- Median 4.8 years
Methodological detailspropensity score-adjusted
- Propensity score-adjusted
Main finding
As reported in the abstract
Interaction with revascularization for mortality
- Viable segments × revascularization · no interaction
- interaction HR 1.09; P = 0.211
- Duke Jeopardy Score × revascularization · no interaction
- interaction HR 0.93; P = 0.245
- Early revascularization, ≥3 jeopardized but viable segments · mortality
- propensity score-adjusted HR 0.55; P = 0.015
Observational data: associations, not effects.
Further findings
| Outcome | HR | P value |
|---|---|---|
| Mortality with ≥3 jeopardized but viable segments (subgroup) · propensity score-adjusted | 0.55 | P = 0.015 |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Patient-Specific Registration of Segmental Jeopardy and Viability: Novel Method to Guide Revascularization in Ischemic Cardiomyopathy. JACC Cardiovasc Imaging. Published 13 January 2026. doi:10.
Summarised from the published abstract; every number is checked against it