Arrhythmias & electrophysiology
Peak frequency analysis and functional substrate mapping to predict critical isthmus of atypical atrial tachycardia: Findings from a novel automated annotation algorithm to detect near-field signals
Authors' conclusion
A PF annotation algorithm with a cutoff of 280 Hz accurately detects the CI of atypical ATs and accurately predicts deceleration zones during isochronal late activation mapping.
Study context
- Population
- Patients with atypical atrial tachycardia (AT) mapped with high-density mapping during sinus/paced rhythm and AT30 ATs mapped
- Participants
- 25 patients
- Exposure
- Peak frequency (PF) of termination site vs low-voltage zones alone
- Outcome
- PF annotation of low-voltage and deceleration zones in predicting CI and termination sites of atypical ATs
Methodological detailshigh-density mapping
- High-density mapping
Main finding
As reported in the abstract
Peak frequency
P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| PF prediction of termination site | PF AUC 0.83 (95% CI 0.719-0.950; P < .001) · Sensitivity (cutoff 280 Hz) 80.0% · Specificity (cutoff 280 Hz) 78.3% |
Original publication
Peak frequency analysis and functional substrate mapping to predict critical isthmus of atypical atrial tachycardia: Findings from a novel automated annotation algorithm to detect near-field signals. Heart Rhythm. Published 16 January 2025. doi:10.
Summarised from the published abstract; every number is checked against it