Arrhythmias & electrophysiology
Site-Specific Ventricular Tachycardia Inducibility
Authors' conclusion
The PES site can have a marked effect on inducibility of VT in some patients such that PES from the RV apex and outflow regions fails to induce clinically relevant VTs. The frequency with which this occurs is not certain. Stimulation from alternative sites is a reasonable consideration in selected patients.
Study context
- Population
- Patients in whom aggressive programmed electrical stimulation (PES) from traditional RV pacing sites failed to induce ventricular tachycardia (VT), but VT was easily inducible from a nontraditional sitepatients reviewed
- Participants
- 6 patients
- Exposure
- PES from traditional RV pacing sites vs a nontraditional site
- Outcome
- Site that induced VT closer to the likely re-entry circuit region
Main finding
As reported in the abstract
Patients in whom the inducing site was closer to the likely re-entry circuit region
5 of the 6
Observational data: associations, not effects.
Further findings
Initiation of re-entry in computer simulations
- Spatial relation of the pacing site to the entrance and exits of a circuit isthmus influenced initiation of re-entry by an extrastimulus by determining the time available for recovery of excitability at the initial region of block
Original publication
Site-Specific Ventricular Tachycardia Inducibility. JACC Clin Electrophysiol. Published 15 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →