Arrhythmias & electrophysiology
Pentaspline catheter or cryoballoon for pulmonary vein plus posterior wall isolation in persistent atrial fibrillation: 1-Year outcomes
Authors' conclusion
In patients with persistent AF undergoing an index catheter ablation, the pentaspline PFA catheter is safe and effective for PVI + LAPWI. Outcomes after pentaspline PFA catheter ablation at 1 year are favorable and similar to those with the CB-A catheter.
Study context
- Population
- Patients with persistent atrial fibrillation (AF) undergoing first (index) ablation with pulmonary vein isolation (PVI) + left atrial posterior wall isolation (LAPWI), Universitair Ziekenhuis Brussel, Belgium, 2021–2023
- Participants
- 160 patients
- Exposure
- Pentaspline pulsed field ablation (PFA) vs cryoballoon ablation (CB-A) for PVI + LAPWI
- PFAn = 80
- CB-An = 80reference
- Outcome
- Freedom from recurrent atrial tachyarrhythmias
- Follow-up
- 1 year
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
P = 0.63
Observational data: associations, not effects.
Further findings
Acute procedural success (PVI + LAPWI)
- PVI + LAPWI performed with success, isolation confirmed at postprocedure high-density mapping in all
- 160 (100%)
Procedure, left atrium dwell and fluoroscopy times
- PFA associated with shorter skin-to-skin procedure time, left atrium dwell time and fluoroscopy time vs CB-A
Original publication
Pentaspline catheter or cryoballoon for pulmonary vein plus posterior wall isolation in persistent atrial fibrillation: 1-Year outcomes. Heart Rhythm. Published 16 December 2024. doi:10.
Summarised from the published abstract; every number is checked against it