Coronary disease & ACS

Percutaneous Coronary Intervention Outcomes by 5 Major Race and Ethnic Subgroups

JACC AdvPublished retrospective cohort study

Authors' conclusion

Significant racial and ethnic disparities exist in 1-year PCI outcomes, with South Asian patients exhibiting favorable outcomes compared with White patients, and Black patients experiencing worse outcomes. Baseline comorbidities and estimated SES do not fully explain these disparities, suggesting that targeted strategies are needed to address the multifactorial influences on PCI outcomes across racial and ethnic groups.

Study context

Population
Patients undergoing percutaneous coronary intervention (PCI) from 2012 to 2022, stratified by race/ethnicity and matched to median household income based on U.S. Census Zone Improvement Plan code datapatients included
Participants
21,236 patients
Exposure
PCI outcomes across 5 racial and ethnic groups-White, Black, Hispanic, South Asian, and East Asian populations-while accounting for comorbidities and socioeconomic status (SES)
  • Whiten = 47.8%reference
  • Blackn = 11.3%
  • Hispanicn = 18.0%
  • South Asiann = 20.7%
  • East Asiann = 2.2%
Outcome
major adverse cardiovascular events (MACE)
Follow-up
1-year

Main finding

As reported in the abstract

Adjusted hazard ratio

0.62

P < 0.001

South Asian · significantly lower major adverse cardiovascular events (MACE)

Adjusted hazard ratio

1.27

P = 0.032

Black · higher risk of MACE

Observational data: associations, not effects.

Original publication

Percutaneous Coronary Intervention Outcomes by 5 Major Race and Ethnic Subgroups. JACC Adv. Published 13 May 2025. doi:10.1016/j.jacadv.2025.101767

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