Coronary disease & ACS

Socioeconomic disparities in the management and outcomes of acute myocardial infarction

HeartPublished Retrospective cohort study

Main finding · In-hospital mortalityResult — go to the resultOdds ratio 1.10 95% CI 1.01–1.19

Authors' conclusion

Patients with a higher deprivation score were more often from an ethnic-minority background, more likely to suffer in-hospital mortality or MACE when compared with the most affluent quintile, and this relationship was stronger in ethnic minorities compared with White patients.

Study context

Population
Patients with acute MI in the UK Myocardial Ischaemia National Audit Project (MINAP) registry, by Index of Multiple Deprivation quintile
Participants
370,064 patients
Exposure
Most deprived (Q5) vs most affluent (Q1) Index of Multiple Deprivation (IMD) quintile; ethnic-minority vs white patients
Outcome
In-hospital mortality
Methodological detailsnational registry (MINAP)
  • National registry (MINAP)

Main finding

As reported in the abstract

Odds ratio

1.10

95% CI 1.01–1.19

P = 0.025

Q5vs Q1
OR 1.10 (95% CI 1.01–1.19); P = 0.025

Observational data: associations, not effects.

Further findings

OutcomeOR (95% CI)P value
MACEQ5vs Q11.07 (1.00–1.15)P = 0.048

Major adverse cardiovascular event (MACE) in Q5, by ethnicity

OR (95% CI)P value
Ethnic-minorityEthnic-minority patients in Q51.40 (1.00–1.95)P = 0.048
WhiteWhite patients in Q51.05 (0.98–1.13)P = 0.027
OutcomeQ1Q5White
Ethnic-minority background by IMD quintile4%15%— not stated in the abstract
In-hospital mortality, Black vs White, Q1 (subgroup)— not stated in the abstract— not stated in the abstract0.062 (95% CI 0.059–0.066)
In-hospital mortality, Black vs White, Q5 (subgroup)— not stated in the abstract— not stated in the abstract0.065 (95% CI 0.061–0.069)

— not stated in the abstract

  • In-hospital mortality, Black vs White, Q1 (subgroup): Black 0.079 (95% CI 0.046–0.112)
  • In-hospital mortality, Black vs White, Q1 (subgroup): Black: p<0.001; White: p<0.001
  • In-hospital mortality, Black vs White, Q5 (subgroup): Black 0.065 (95% CI 0.054–0.077)
  • In-hospital mortality, Black vs White, Q5 (subgroup): Black: p<0.001; White: p<0.001

Original publication

Socioeconomic disparities in the management and outcomes of acute myocardial infarction. Heart. Published 9 August 2023. doi:10.1136/heartjnl-2023-322601

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