Valvular & structural heart disease
Percutaneous Edge-to-Edge Repair of Atrioventricular Valves in Congenital Heart Disease: A Multicenter Clinical Experience
Authors' conclusion
TEER for carefully selected patients with CHD and severe AVVR was safe and effective with notable improvements in regurgitation and clinical symptoms.
Study context
- Population
- Patients with congenital heart disease (CHD) and symptomatic 3+ or 4+ atrioventricular valve regurgitation (AVVR) undergoing atrioventricular transcatheter edge-to-edge repair (TEER)18 reached 6-month follow-up
- Participants
- 20 patients
- Outcome
- AVVR reduced from 3+/4+ at baseline to mild-to-moderate (1+ to 2+)
- Follow-up
- 30 days
Methodological detailsmulticentre, 5 medical centers
- Multicentre
- 5 medical centers
Main finding
As reported in the abstract
- Patients with AVVR reduced to mild-to-moderate (1+ to 2+)
- 19 (95.0%)
- P value
- P < 0.001
Observational data: associations, not effects.
Further findings
NYHA class III-IV · 30 days
- NYHA class III-IV at baseline
- 18 (90.0%)
- NYHA class III-IV at 30 days
- 10.5%
Death (intractable HF) · first 30 days
- Deaths
- 1 (5.0%)
Original publication
Percutaneous Edge-to-Edge Repair of Atrioventricular Valves in Congenital Heart Disease: A Multicenter Clinical Experience. JACC Adv. Published 4 December 2025. doi:10. 1016/ j. jacadv. 2025. 102408
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