Valvular & structural heart disease
Percutaneous paravalvular leak closure after transcatheter aortic valve implantation: the international PLUGinTAVI Registry
Authors' conclusion
Percutaneous PVL closure is a feasible and safe option for treating post-TAVI leaks.
Study context
- Population
- Patients undergoing percutaneous paravalvular leak (PVL) closure after transcatheter aortic valve implantation (TAVI), 2018–2022
- Participants
- 45 patients
- Outcome
- Successful PVL closure
Methodological detailsinternational, 14 hospitals across Europe and North America
- International
- 14 hospitals across Europe and North America
Main finding
As reported in the abstract
Successful PVL closure
94%
Regurgitation reduced to ≤mild
91%
Observational data: associations, not effects.
Further findings
Long-term follow-up · 21.7±16.2 months
- All-cause mortality
- 14%
- HF hospitalisation rate (before → after)
- from 40% to 6%
- Improvement in functional status
Safety
- Severe adverse events
- 11%
- In-hospital deaths
- 0
Original publication
Percutaneous paravalvular leak closure after transcatheter aortic valve implantation: the international PLUGinTAVI Registry. EuroIntervention. Published 7 August 2023. doi:10.
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