Heart failure & cardiomyopathies
Percutaneous Thoracic Duct Externalization and Autotransfusion in Patients With Lymphatic Failure Due to Elevated Central Venous Pressure
Authors' conclusion
Thoracic duct drainage with autotransfusion can improve fluid status and end-organ function without significant complications and presents a new therapeutic option.
Study context
- Population
- Patients with lymphatic failure due to elevated central venous pressure undergoing percutaneous thoracic duct drainage with autotransfusion
- Participants
- 8 patients
- Outcome
- Outcomes after thoracic duct drainage with autotransfusion
Methodological detailsretrospective review of medical records
- Retrospective review of medical records
Main finding
As reported in the abstract
- Survived to decannulation
- 7 (87.5%)
- Median duration of autotransfusion
- 11.5 days (range, 6-126)
- Creatinine, median, before vs after
- 0.63 (0.3-2.4) to 0.36 (0.16-0.8) mg/dL (P=0.017)
- Significant reduction in weight
- P=0.017
- Significant reduction in drainage output
- P=0.017
Observational data: associations, not effects.
Further findings
Baseline central venous pressure
- Median central venous pressure
- 15.5 mm Hg (range, 12-28)
Intraprocedural or autotransfusion-related deaths
- No intraprocedural or autotransfusion-related deaths
Original publication
Percutaneous Thoracic Duct Externalization and Autotransfusion in Patients With Lymphatic Failure Due to Elevated Central Venous Pressure. Circ Cardiovasc Interv. Published 4 September 2025. doi:10. 1161/ circinterventions. 125. 015336
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