Heart failure & cardiomyopathies

Percutaneous Thoracic Duct Externalization and Autotransfusion in Patients With Lymphatic Failure Due to Elevated Central Venous Pressure

Circ Cardiovasc IntervPublished Retrospective case series

Authors' conclusion

Thoracic duct drainage with autotransfusion can improve fluid status and end-organ function without significant complications and presents a new therapeutic option.

Study context

Population
Patients with lymphatic failure due to elevated central venous pressure undergoing percutaneous thoracic duct drainage with autotransfusion
Participants
8 patients
Outcome
Outcomes after thoracic duct drainage with autotransfusion
Methodological detailsretrospective review of medical records
  • Retrospective review of medical records

Main finding

As reported in the abstract

Survived to decannulation
7 (87.5%)
Median duration of autotransfusion
11.5 days (range, 6-126)
Creatinine, median, before vs after
0.63 (0.3-2.4) to 0.36 (0.16-0.8) mg/dL (P=0.017)
Significant reduction in weight
P=0.017
Significant reduction in drainage output
P=0.017

Observational data: associations, not effects.

Further findings

Baseline central venous pressure

Median central venous pressure
15.5 mm Hg (range, 12-28)

Intraprocedural or autotransfusion-related deaths

No intraprocedural or autotransfusion-related deaths

Original publication

Percutaneous Thoracic Duct Externalization and Autotransfusion in Patients With Lymphatic Failure Due to Elevated Central Venous Pressure. Circ Cardiovasc Interv. Published 4 September 2025. doi:10.1161/circinterventions.125.015336

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