Periprocedural myocardial infarction and injury in elective coronary stenting
Authors' conclusion
Periprocedural MI and injury are frequent complications of elective PCI associated with an increased rate of cardiovascular events at 30 days and 1 year.
Study context
- Population
- Patients undergoing elective percutaneous coronary intervention (PCI) with negative admission troponin, 1 January 2014 to 31 December 2015
- Participants
- 1,390 patients
- Exposure
- Periprocedural myocardial infarction (MI) and myocardial injury vs none
- Outcome
- Composite of:
- Periprocedural MI (Type 4a MI)
- Stent thrombosis (Type 4b MI)
- Myocardial injury (Third universal definition of MI)
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
Incidence of primary endpoint
Primary endpoint
28.7%
Type 4a MI
7.0%
Type 4b MI
0.14%
Myocardial injury
21.6%
Observational data: associations, not effects.
Further findings
| Outcome | Periprocedural MI and myocardial injury | No periprocedural MI or injury | Estimate | P value | |
|---|---|---|---|---|---|
| CV events · 30 days | 5.5% | 1.2% | adjHR 3.8 (95% CI 1.9–6.9) | P < 0.001 | |
| Ischaemic events · 30 days | 3.2% | 0.6% | HR 5.9 (95% CI 2.9–20) | P < 0.0001 | |
| Ischaemic events · 1 year | adjHR 1.7 (95% CI 1.1–2.6) | P = 0.004 | |||
| 0.050.21520Ratio (log scale) |
Independent risk factors for primary endpoint
- Left main PCI, total stent length >30 mm, multiple stenting, CKD (eGFR <60 mL/min), age >75 years
Original publication
Periprocedural myocardial infarction and injury in elective coronary stenting. Eur Heart J. Published 20 January 2018. doi:10.
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