Heart failure & cardiomyopathies
Phenotyping Congestion in Acute Heart Failure by Renal Flow and Right Heart to Pulmonary Circulation Coupling
Authors' conclusion
In AHF, the renal venous flow pattern combined with a right heart study phenotypes congestion and clinical evolution. Keys to renal flow disruption are an impaired right atrial dynamics and RV-Pc uncoupling.
Study context
- Population
- Patients with acute HF
- Participants
- 119 patients
- Outcome
- Determinants of renal venous stasis index (RVSI), a quantitative parameter of renal congestion
Main finding
As reported in the abstract
Determinants of RVSI
- Tricuspid annular plane systolic excursion (TAPSE)/PASP, right atrial peak longitudinal strain and inferior vena cava (IVC) diameter were independent determinants of renal venous stasis index (RVSI)
- Renal Doppler congestion associated with reduced right ventricular (RV) function, impaired RV to pulmonary circulation coupling, reduced RA strain and signs of volume overload
- No differences in haemodynamics or baseline renal function across intra-renal venous flow patterns
Observational data: associations, not effects.
Further findings
Composite of cardiac death, HF hospitalisation and haemodialysis
- RVSI was the only variable predicting the composite outcome
Echo-derived right heart score (4 variables) for kidney congestion
- Good accuracy in identifying kidney congestion
Original publication
Phenotyping Congestion in Acute Heart Failure by Renal Flow and Right Heart to Pulmonary Circulation Coupling. ESC Heart Fail. Published 24 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →