Arrhythmias & electrophysiology
Pilot Study of Early Catheter Ablation and Neurological Outcomes in Atrial Fibrillation-Related Stroke: RESCUE-STROKE
Authors' conclusion
Early CA following the diagnosis of AF after a stroke is associated with significant improvement in neurologic outcomes, adverse events, and AF-related outcomes. Because of important differences in the study populations, it is uncertain whether these are directly attributable to early CA. Patients with stroke and AF may benefit from earlier CA, but additional studies are needed.
Study context
- Population
- Patients hospitalized with stroke and new-onset atrial fibrillation (AF) from 2021 to 2023
- Participants
- 36 vs 36
- Exposure
- Early rhythm control with CA vs routine care after stroke with new-onset AF
- CAn = 36
- Routine caren = 36
- Outcome
- Modified Rankin score
- Follow-up
- Admission
Main finding
As reported in the abstract
CA
4.5
mean · SD 1.0
Routine care
4.4
mean · SD 1.0
P = 0.717
Observational data: associations, not effects.
Further findings
Time to rhythm control · faster with CA
P < 0.001
Continued AF freedom · 12 months
P < 0.001
Mean
| Outcome | CA | Routine care | P value |
|---|---|---|---|
| Modified Rankin score · dischargeSimilar | 4.23 (SD 0.7) | 4.2 (SD 0.8) | P = 0.656 |
| Modified Rankin score · 6 monthsLower with CA | 2.0 (SD 0.7) | 3.5 (SD 0.8) | P < 0.001 |
| Modified Rankin score · 12 monthsLower with CA | 1.1 (SD 0.8) | 3.0 (SD 1.0) | P < 0.001 |
| Number of hospitalizationsFewer with CA | 0.4 (SD 0.8) | 1.8 (SD 1.5) | P < 0.001 |
Safety
Repeat strokes · fewer with CA
P = 0.091
Major bleeding · fewer with CA
P = 0.126
Mortality · fewer with CA
P < 0.001
Original publication
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