Heart failure & cardiomyopathies
Poor Cardiovascular Outcomes of Underweight Abdominal Obesity in the Entire Population of Newly Diagnosed Heart Failure
Authors' conclusion
The cardiovascular prognosis was significantly worse in the underweight group than in the obese group, especially in the underweight abdominal obesity group. Even in the same BMI group, the prognosis is worse in the group with abdominal obesity.
Study context
- Population
- Patients newly diagnosed with heart failure (HF), Republic of Korea, 2012–2021
- Participants
- 999,127 patients
- Exposure
- Body mass index (BMI) and waist circumference (WC) categories
- Outcome
- CV outcomes (hospitalization, all-cause death, CV death, acute MI, AF, composite cardiac events) by BMI and WC
Methodological detailsentire population of the Republic of Korea
- Entire population of the Republic of Korea
Main finding
As reported in the abstract
- Underweight: significantly increased hospitalization, all-cause death, CV death, acute MI, AF and composite cardiac events vs other groups
- P value < 0.05
- Abdominal obesity in normal, overweight and obese: significantly high HR in almost all CV events
- P value < 0.05
Observational data: associations, not effects.
Further findings
- Obese share of newly diagnosed HF population · 2012–2021
- 47.1%
Original publication
Poor Cardiovascular Outcomes of Underweight Abdominal Obesity in the Entire Population of Newly Diagnosed Heart Failure. ESC Heart Fail. Published 26 September 2025. doi:10.
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