Valvular & structural heart disease
Portal vein Doppler tracks volume status in patients with severe tricuspid regurgitation: a proof-of-concept study
Authors' conclusion
This proof-of-concept study suggests that PVD is the only sonographic marker that can track volume removal in severe TR, offering a potential indicator for decongestion in this population.
Study context
- Population
- Patients with severe tricuspid regurgitation (TR) undergoing decongestive therapy
- Participants
- 42 patients
- Exposure
- PVD vs Intra-renal venous Doppler (IRVD) for tracking decongestion
- Outcome
- Change in PVD and IRVD indices during volume removal
- Follow-up
- After volume removal
Methodological detailsproof-of-concept
- Proof-of-concept
Main finding
As reported in the abstract
Improvement in Doppler indices after volume removal
Improvement in Doppler indices after volume removal PVD 47 ± 44 % · IRVD 0.54 ± 0.22
PVPF before PVD 130 ± 39%
Partial improvement
Complete improvement
Before IRVD 0.72 ± 0.08
- PVD vs IRVD: P < 0.001 — proportion improved
- Portal vein pulsatility fraction (PVPF) improved after volume removal
- P < 0.001
- IRVD improved after volume removal
- P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | PVD |
|---|---|
| Prediction of ≥5 L negative fluid balance | |
| AUC | 0.83 |
- Prediction of ≥5 L negative fluid balance — PVD the only predictor
- P = 0.001
Original publication
Portal vein Doppler tracks volume status in patients with severe tricuspid regurgitation: a proof-of-concept study. Eur Heart J Acute Cardiovasc Care. Published 12 May 2024. doi:10.
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