Heart failure & cardiomyopathies

Pragmatic Screening for Heart Failure in the General Population Using an Electrocardiogram-Based Neural Network

ESC Heart FailPublished Diagnostic accuracy study

Authors' conclusion

Using a CNN build on digital ECGs only and requiring no additional input, we derived a screening tool for heart failure in the general population.

Study context

Population
Randomly selected inhabitants of Hamburg aged 45–75 years318 (6.0%) with HF
Participants
5,299 participants
Comparison
ECG-based convolutional neural network (CNN) vs logistic regression and random forest models using HF risk variables
Outcome
Discrimination of participants with vs without HF (diagnosed per current guidelines)
Methodological detailsprospective, observational, population-based (Hamburg-City-Health-Study)
  • Prospective
  • Observational
  • Population-based (Hamburg-City-Health-Study)

Performance

As reported in the abstract

HF detection
Test or modelAUCSensitivitySpecificity
CNN0.750.670.69
Logistic regression0.770.630.76
Random forest0.790.670.72

AUC

CNN0.75
Logistic regression0.77
Random forest0.79

Sensitivity

CNN0.67
Logistic regression0.63
Random forest0.67

Specificity

CNN0.69
Logistic regression0.76
Random forest0.72

Original publication

Pragmatic Screening for Heart Failure in the General Population Using an Electrocardiogram-Based Neural Network. ESC Heart Fail. Published 8 December 2022. doi:10.1002/ehf2.14263

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