Randomised controlled trial
Pragmatic Trial of Hospitalization Rate in Chronic Kidney Disease
- Randomised controlled trial
- open-label
- cluster-randomised
- pragmatic
Authors' conclusion
In this pragmatic trial involving patients with the triad of chronic kidney disease, type 2 diabetes, and hypertension, the use of an EHR-based algorithm and practice facilitators embedded in primary care clinics did not translate into reduced hospitalization at 1 year.
Study context
- Population
- Patients with CKD, T2DM and hypertension (kidney-dysfunction triad) treated at 141 primary care clinics
- Participants
- 11,182 patients · 141 clinics
- Comparison
- Intervention vs Usual care
- Interventionn = 5,690
- Usual caren = 5,492reference
- Primary endpoint
- Hospitalization for any cause
- Follow-up
- 1 year
Primary result
Hospitalization rate
Between-group difference
0.4 percentage points
P = 0.58
By group
As reported in the abstract
Secondary outcomes
ED visits, readmissions, CV events, dialysis, all-cause death
- Risks similar in the two groups
Safety
AKI · other adverse events similar in the trial groups
Original publication
Pragmatic Trial of Hospitalization Rate in Chronic Kidney Disease. N Engl J Med. Published 4 April 2024. doi:10.1056/nejmoa2311708
Summarised from the published abstract; every number is checked against it