Arrhythmias & electrophysiologyCohort study
Pre-eclampsia and long-term risk of arrhythmias
- Nationwide registry-based observational cohort study
- Danish nationwide registries
Authors' conclusion
Pre-eclamptic women were associated with a significantly and at hitherto unknown long-term increased rate of arrhythmias.
Study context
- Population
- Primiparous women giving birth in Denmark, 1997–2016 (median age 28 years)
- Participants
- 523,271 women
- Exposure
- Pre-eclampsia (PE) vs no PE during primiparous pregnancy
- PEn = 23,367
- Outcome
- Incident arrhythmia
- Follow-up
- Median 10.1 years
Main finding
As reported in the abstract
Arrhythmias
PE vs No PEAdjusted hazard ratio (95% CI)
cardiac arrest, VT/VF or ICD implantation
1.60(1.14–2.24)
advanced second- or third-degree AV block, sinoatrial dysfunction or pacemaker implantation
1.48(0.97–2.23)
supraventricular tachyarrhythmias or extra systoles
1.34(1.19–1.51)
all arrhythmias above
1.37(1.23–1.54)
Observational data: associations, not effects.
Original publication
Pre-eclampsia and long-term risk of arrhythmias. Eur J Prev Cardiol. Published 17 May 2024. doi:10.1093/eurjpc/zwae176
Summarised from the published abstract; every number is checked against it