Arrhythmias & electrophysiology
Demonstration of Arrhythmia Substrate-Associated Dispersion of Repolarization by Epicardial Unipolar Mapping in Brugada Syndrome
Authors' conclusion
Bipolar DP-related prominent unipolar J waves and steep repolarization gradients may be more specific for characterizing BrS than for overt cardiomyopathy. Ventricular arrhythmias in BrS are associated with a steep repolarization gradient, indicating phase 2 re-entry as a possible cause.
Study context
- Population
- Patients with Brugada syndrome or cardiomyopathy undergoing epicardial mapping
- Participants
- 8 vs 6
- Comparison
- Brugada syndrome (BrS) vs cardiomyopathy
- BrSn = 8
- Cardiomyopathyn = 6reference
- Outcome
- Unipolar J-wave amplitude at bipolar DP sites and RT dispersion index, BrS vs cardiomyopathy (baseline)
- Follow-up
- Baseline
Main finding
As reported in the abstract
baseline
| Group | Sensitivity of J-wave amplitude ≥0.42 mV for BrS | Specificity of J-wave amplitude ≥0.42 mV for BrS |
|---|---|---|
| BrS | 99.1% | 100% |
BrS
Sensitivity of J-wave amplitude ≥0.42 mV for BrS99.1%
Specificity of J-wave amplitude ≥0.42 mV for BrS100%
Original publication
Demonstration of Arrhythmia Substrate-Associated Dispersion of Repolarization by Epicardial Unipolar Mapping in Brugada Syndrome. JACC Clin Electrophysiol. Published 16 May 2024. doi:10.
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