Coronary disease & ACS

Prediction of fractional flow reserve using intravascular ultrasound

EuroInterventionPublished Diagnostic accuracy study

Authors' conclusion

The IQ-FFR is a promising method to identify coronary lesions requiring revascularisation and to predict the FFR after stent implantation.

Study context

Population
Coronary lesions with stenosis (25–99%) and intravascular ultrasound (IVUS) and fractional flow reserve (FFR) measured just before and after stent implantation
Participants
270 coronary lesions
Comparison
IVUS-derived IQ-FFR vs wire-derived FFR
Outcome
Agreement of IQ-FFR with wire-derived FFR
Methodological detailsprospective, single-centre
  • Prospective
  • Single-centre

Performance

As reported in the abstract

Test or modelCorrelation with wire-derived FFR (r)Accuracy predicting post-stent FFR >/<0.80
IQ-FFR0.89687.5%

IQ-FFR

Correlation with wire-derived FFR (r)0.896
Accuracy predicting post-stent FFR >/<0.8087.5%

Original publication

Prediction of fractional flow reserve using intravascular ultrasound. EuroIntervention. Published 7 October 2024. doi:10.4244/eij-d-24-00010

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