Heart failure & cardiomyopathies
Predictive Value of Right Ventricular Sensing During Cardiac Device Implantation to Diagnose Cardiac Amyloidosis
Authors' conclusion
In patients with ILVWT, a relatively low RVSens (≤11 mV) during device implantation was independently associated with CA diagnosis
Study context
- Population
- Patients with increased left ventricular (LV) wall thickness (≥12 mm), preserved LV function and no significant AS undergoing CIED implantation150 with cardiac amyloidosis (CA)
- Participants
- 218 patients
- Comparison
- RVSens ≤11 mV during CIED implantation for diagnosis of cardiac amyloidosis
- Outcome
- Diagnosis of cardiac amyloidosis
Methodological detailsretrospective, 2 French referral centres, consecutive patients
- Retrospective
- 2 French referral centres
- Consecutive patients
Performance
As reported in the abstract
Cardiac amyloidosis diagnosis
| Test or model | Sensitivity | Specificity | AUC |
|---|---|---|---|
| RVSens ≤11 mV | 84% | 79.4% | 0.878 |
RVSens ≤11 mV
Sensitivity84%
Specificity79.4%
AUC0.878
Further findings
Timing of device implantation
- Implanted before ILVWT diagnosis
- 10 (4.6%)
- Implanted during same hospitalization
- 131 (60.1%)
- Implanted in subsequent hospitalization
- 77 (35.3%)
Original publication
Predictive Value of Right Ventricular Sensing During Cardiac Device Implantation to Diagnose Cardiac Amyloidosis. JACC Clin Electrophysiol. Published 4 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →