Heart failure & cardiomyopathies

Predictive Value for Mortality of Left Ventricular Wall Thickness in Dilated Cardiomyopathy

ESC Heart FailPublished Prognostic cohort study

Authors' conclusion

PWT measured by CMR is an independent predictor of all-cause mortality in DCM patients. However, there was no significant correlation between septum wall thickness and mortality.

Study context

Population
Dilated cardiomyopathy (DCM) patients who underwent cardiac magnetic resonance (CMR) and completed regular follow-up
Participants
161 patients
Comparison
Death vs non-death
  • Deathn = 41
Outcome
All-cause mortality
Follow-up
Median 47 months (IQR 32-57 months)

Performance

As reported in the abstract

median 47 months

Hazard ratio

0.086

95% CI 0.665–0.976P < 0.05

Posterior wall thickness (PWT)

Hazard ratio

0.001

95% CI 0.000–0.502P < 0.05

RWTPW

Death

24.8%

41

Further findings

LVDd

P = 0.025

PWT

P < 0.001

IVST

P = 0.005

LVM/LVEDV ratio

P < 0.001

Presence of LGE

P = 0.048

OutcomeDeathNon-deathP value
RWTPW0.15 (range 0.11–0.19)0.20 (range 0.15–0.25)P < 0.001
RWTIVS0.22 (range 0.17–0.26)0.26 (range 0.22–0.31)P < 0.001
LGE extentNot significant4 (range 1–7)2 (range 0–6)P = 0.096

Original publication

Predictive Value for Mortality of Left Ventricular Wall Thickness in Dilated Cardiomyopathy. ESC Heart Fail. Published 22 September 2023. doi:10.1002/ehf2.14534

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