Valvular & structural heart disease
Predictors of underexpansion after transcatheter aortic valve implantation with the ACURATE neo valve
Authors' conclusion
Annular calcium volume was shown to be associated with underexpanded ACURATE THVs, while post-dilatation may reduce valve deformation.
Study context
- Population
- Patients undergoing transcatheter aortic valve implantation (TAVI) with an ACURATE transcatheter heart valve (THV), January 2014–December 2022, with available computed tomography angiography (CTA) and procedural fluoroscopyeligible of 3,027
- Participants
- 480 patients
- Exposure
- Underexpanded vs expanded ACURATE THV
- Underexpandedn = 74
- Expandedn = 406reference
- Outcome
- Procedural factors (mainly preprocedural CTA) associated with valve underexpansion
Methodological detailssingle-centre, observational
- Single-centre
- Observational
Main finding
As reported in the abstract
Factors associated with THV underexpansion
Odds ratio (95% CI)P value
Annulus calcium volume
2.333(1.331–4.089)
P = 0.003Post-dilatation
0.350(0.203–0.602)
P < 0.001Observational data: associations, not effects.
Further findings
Sensitivity analysis: annulus calcium volume >54 mm³ (dichotomised)
| OR (95% CI) | P value | ||
|---|---|---|---|
| Annulus calcium volume >54 mm³For underexpansion | 2.38 (1.37–4.19) | P = 0.002 | |
| 0.20.5125Odds ratio (log scale) |
Original publication
Predictors of underexpansion after transcatheter aortic valve implantation with the ACURATE neo valve. EuroIntervention. Published 15 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →