Premorbid physical activity and prognosis after incident myocardial infarction: The atherosclerosis risk in communities study
Main finding · Composite outcomeResult — go to the resultAdjusted hazard ratio 0.80 CI 0.67–0.96Authors' conclusion
Premorbid PA was associated positively with post-MI cardiovascular health.
Study context
- Population
- ARIC study participants with incident myocardial infarction (MI) (mean age 73 years at MI, 54% men, 21% Black); Physical activity (PA) assessed on average 11.9 years before MI
- Participants
- 1,111 participants
- Exposure
- Highest vs lowest tertile of premorbid total physical activity
- Outcome
- Composite of:
- Mortality
- Recurrent MI
- Stroke after index MI
- Follow-up
- Median 4.6 years
Methodological detailsmultivariable Cox models
- Multivariable Cox models
Main finding
Composite outcome
Adjusted hazard ratio
0.80
CI 0.67–0.96
By group
Highest tertile vs Lowest tertile
aHR 0.80 (CI 0.67–0.96)
As reported in the abstract
- Composite outcome developed (all participants)
- 823 (74%)
Observational data: associations, not effects.
Further findings
| Outcome | aHR | |
|---|---|---|
| Recurrent MI | 0.64 (CI 0.44–0.93) | |
| Composite outcome · first year after MIAssociation strongest in first year | 0.66 (95% CI 0.47–0.91) | |
| 0.512Adjusted hazard ratio (log scale) |
Domain-specific PA (sport, work)
- Similar results for sport and work PA
Original publication
Premorbid physical activity and prognosis after incident myocardial infarction: The atherosclerosis risk in communities study. Am Heart J. Published 7 May 2024. doi:10.
Summarised from the published abstract; every number is checked against it