Valvular & structural heart disease
Preoperative computed tomography-imaging with patient-specific computer simulation in transcatheter aortic valve implantation: Design and rationale of the GUIDE-TAVI trial
Study context
- Population
- Patients accepted for Transcatheter Aortic Valve Implantation (TAVI) by the Heart Teamplanned
- Participants
- 227 vs 227
- Planned comparison
- Computed tomography (CT)-based patient-specific computer simulation (FEops HEARTGuide (FHG)) plus routine CT vs routine CT alone before TAVI
- FHGn = 227
- No FHGn = 227reference
- Primary endpoint
- Incidence of mild to severe PVR (VARC-3)
Methodological detailsinternational, multicentre, Secondary endpoints: new conduction disorders requiring permanent pacemaker, preoperative vs final valve size, target vs final implantation depth, change of preoperative decision, failure to implant valve, early safety composite, quality of life
- International
- Multicentre
- Secondary endpoints: new conduction disorders requiring permanent pacemaker, preoperative vs final valve size, target vs final implantation depth, change of preoperative decision, failure to implant valve, early safety composite, quality of life
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Preoperative computed tomography-imaging with patient-specific computer simulation in transcatheter aortic valve implantation: Design and rationale of the GUIDE-TAVI trial. Am Heart J. Published 30 December 2023. doi:10.
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