Valvular & structural heart disease
Preoperative sST2 Levels Relate to Myocardial Remodeling and Cardiac Function Improvement After Cardiac Valve Surgery
Authors' conclusion
Preoperative sST2 levels are related to early postoperative myocardial remodelling and have a predictive value for the improvement of cardiac function 1 month after surgery.
Study context
- Population
- Patients with valvular heart disease undergoing heart valve surgery, General Hospital of Northern Theatre Command, July 2019 to June 2020
- Participants
- 156 patients
- Outcome
- Association of preoperative sST2 with postoperative remodelling and cardiac function
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Preoperative sST2 vs early postoperative LV end-systolic volume (b)
- −0.136, P = 0.035
- Preoperative sST2 vs early postoperative LV end-diastolic volume (b)
- −0.225, P = 0.036
- Preoperative sST2 vs early postoperative left ventricular ejection fraction (LVEF) (b)
- 0.056, P = 0.008
- LVEF at 1 month vs preoperative sST2 (r)
- −0.234, P = 0.023
- LVEF reduction at 1 month vs preoperative sST2 (r)
- −0.316, P = 0.002
- AUC of preoperative sST2 for LVEF reduction at 1 month
- 0.646
- Sensitivity
- 0.357
- Specificity
- 0.918
Observational data: associations, not effects.
Further findings
Factors correlated with preoperative sST2
- LV end-systolic volume (b)
- 0.125, P = 0.004
- AF (b)
- 7.933, P = 0.003
- CAD (b)
- 5.826, P = 0.043
Original publication
Preoperative sST2 Levels Relate to Myocardial Remodeling and Cardiac Function Improvement After Cardiac Valve Surgery. ESC Heart Fail. Published 11 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →