Acute cardiac care & resuscitation

Presentation and Outcomes of Patients With Preoperative Critical Illness Undergoing Cardiac Surgery

JACC AdvPublished Retrospective cohort study

Authors' conclusion

Nearly 1 in 12 contemporary CICU patients receive cardiac surgery. Despite high preoperative disease severity, CICU admissions undergoing cardiac surgery had a comparable mortality rate to CICU patients overall

Study context

Population
Cardiac ICU admissions referred for cardiac surgery, 2017 to 2020, 29 centres
Participants
887 vs 10,321
Exposure
Cardiac surgery vs all cardiac intensive care unit (CICU) admissions
  • Cardiac surgeryn = 887
  • All CICU admissionsn = 10,321reference
Outcome
In-hospital mortality
Methodological detailsmulticentre (29 centres)
  • Multicentre (29 centres)

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

Cardiac surgery procedures

CABG
406 (46%)
Transplants or ventricular assist devices
201 (23%)
Valve surgeries
171 (19%)
Other procedures
109 (12%)

Indications for CICU admission

Shock
33.5%
Respiratory insufficiency
24.9%

Preoperative CICU therapies

Vasoactive therapy
52.2%
Mechanical circulatory support
35.9%
Renal replacement
8.2%
Mechanical ventilation
35.7%
High-flow nasal cannula or noninvasive positive pressure ventilation
17.5%

Predictors of mortality (multivariable)

Pre-op mechanical circulatory support and renal replacement therapy associated with mortality
Respiratory support and vasoactive therapy not associated with mortality
  • Multivariable adjustment

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Presentation and Outcomes of Patients With Preoperative Critical Illness Undergoing Cardiac Surgery. JACC Adv. Published 8 March 2023. doi:10.1016/j.jacadv.2023.100260

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