Acute cardiac care & resuscitation
Pressure-Adjusted Heart Rate by Echocardiography and Mortality in the Cardiac Intensive Care Unit
Main finding · In-hospital mortalityResult — go to the resultAdjusted odds ratio 1.03 95% CI 1.01–1.05Authors' conclusion
PAHR is a readily determinable composite measure of cardiovascular status that enhances clinical risk stratification of critically ill patients, performing better than MAP, HR, and Modified Shock Index. Among CICU patients, higher PAHR by TTE was associated with greater mortality.
Study context
- Population
- Patients with a transthoracic echocardiogram (TTE) within 24 hours of admission to an academic cardiac intensive care unit (CICU)
- Participants
- 5,411 patients
- Exposure
- Per 1 BPM higher PAHR obtained from TTE
- Outcome
- In-hospital mortality
Methodological detailsacademic CICU (2007-2018)
- Academic CICU (2007-2018)
Main finding
As reported in the abstract
Adjusted odds ratio
1.03
95% CI 1.01–1.05
P = 0.001
Each 1 BPM higher PAHR
adjusted OR 1.03 (95% CI 1.01–1.05); P = 0.001
Each 1 BPM higher PAHR, as printed
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Adjusted HR (95% CI) | P value | |
|---|---|---|---|
| One-year mortality (secondary outcome)Mortality increased with higher PAHR | 1.03 (1.02–1.04) | P < 0.001 | |
| 0.512Adjusted hazard ratio (log scale) |
| Outcome | Patients who died while hospitalized | Survivors |
|---|---|---|
| Median PAHR by in-hospital death | median 14.3 beats/min | median 6.8 BPM |
- Median PAHR by in-hospital death: P < 0.001
Discrimination of PAHR for in-hospital mortality
- C-statistic
- 0.75
- Moderate discrimination
Original publication
Pressure-Adjusted Heart Rate by Echocardiography and Mortality in the Cardiac Intensive Care Unit. JACC Adv. Published 13 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →