Prevalence and Correlates of Lipoprotein(a) Testing in a Diverse Cohort of U.S. Adults
Authors' conclusion
The prevalence of Lp(a) testing among US adults is exceedingly low, especially for non-Hispanic Black individuals and those with socioeconomic risk. These results underline the importance of emphasizing health equity in Lp(a) testing expansion.
Study context
- Population
- Participants ≥18 years of age from the All of Us Research Study who shared electronic medical record information through 2022participants who shared electronic medical record information through 2022
- Participants
- 266,612 participants
- Comparison
- Association of demographic, socioeconomic, and clinical variables with Lp(a) testing
- Outcome
- Lp(a) testing
Main finding
As reported in the abstract
Underwent Lp(a) testing
2,172
0.8%
Of those tested, had clinical cardiovascular disease
86%
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| Lp(a) testing by race and ethnicity32% lower odds · multivariable logistic regression | 0.68 (0.58–0.81) | |
| 0.512Odds ratio (log scale) |
Lp(a) testing by socioeconomic factors
| OR (95% CI) | ||
|---|---|---|
| Less than high school education | 0.34 (0.25–0.44) | |
| Unemployment | 0.76 (0.68–0.85) | |
| Disability | 0.77 (0.65–0.91) | |
| 0.20.5125Odds ratio (log scale) |
Lp(a) testing by clinical factors
| OR (95% CI) | ||
|---|---|---|
| non-Lp(a) lipid abnormality | 5.64 (4.72–6.79) | |
| Prevalent cardiovascular disease | 3.21 (2.76–3.74) | |
| 0.10.31310Odds ratio (log scale) |
- Lp(a) testing by socioeconomic factors — lower odds of Lp(a) testing
- 23% to 66%
Baseline characteristics
- Mean age
- 52 years
- Women
- 61%
- non-Hispanic White
- 53%
Original publication
Prevalence and Correlates of Lipoprotein(a) Testing in a Diverse Cohort of U.S. Adults. JACC Adv. Published 30 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →