Heart failure & cardiomyopathies

Prevalence and Prognosis of Frailty in Older Patients with Stage B Heart Failure with Preserved Ejection Fraction

ESC Heart FailPublished Prospective cohort study

Main finding · All-cause mortality or readmissionResult — go to the resultAdjusted risk (fold) 1.53 95% CI 1.11–2.11

Authors' conclusion

Frailty is common in elderly patients with stage B HFpEF. Physical frailty, particularly low physical activity, can independently predict the long-term prognosis in these patients.

Study context

Population
Inpatients aged ≥65 years with stage B heart failure with preserved ejection fraction (HFpEF) (structural or functional abnormalities, left ventricular ejection fraction (LVEF) ≥ 50%, no signs or symptoms)
Participants
520 inpatients
Exposure
Frail vs non-frail
  • Frailn = 145
Outcome
All-cause mortality or readmission
Follow-up
3 years
Methodological details3-year follow-up
  • 3-year follow-up

Main finding

As reported in the abstract

Adjusted risk (fold)

1.53

95% CI 1.11–2.11

P = 0.009

By group

Observational data: associations, not effects.

Further findings

All-cause readmission · 3 years · unadjusted P = 0.029

adjusted risk (fold) 1.52 (1.09–2.11) · P = 0.014

Readmission for non-HF · 3 years · unadjusted P = 0.004

adjusted risk (fold) 1.70 (1.21–2.38) · P = 0.002

OutcomeFrailNon-frail
Prevalence of frailty27.9%— not stated in the abstract

— not stated in the abstract

Original publication

Prevalence and Prognosis of Frailty in Older Patients with Stage B Heart Failure with Preserved Ejection Fraction. ESC Heart Fail. Published 4 January 2023. doi:10.1002/ehf2.14274

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