Heart failure & cardiomyopathies
Prevalence and Prognosis of Frailty in Older Patients with Stage B Heart Failure with Preserved Ejection Fraction
Main finding · All-cause mortality or readmissionResult — go to the resultAdjusted risk (fold) 1.53 95% CI 1.11–2.11Authors' conclusion
Frailty is common in elderly patients with stage B HFpEF. Physical frailty, particularly low physical activity, can independently predict the long-term prognosis in these patients.
Study context
- Population
- Inpatients aged ≥65 years with stage B heart failure with preserved ejection fraction (HFpEF) (structural or functional abnormalities, left ventricular ejection fraction (LVEF) ≥ 50%, no signs or symptoms)
- Participants
- 520 inpatients
- Exposure
- Frail vs non-frail
- Frailn = 145
- Outcome
- All-cause mortality or readmission
- Follow-up
- 3 years
Methodological details3-year follow-up
- 3-year follow-up
Main finding
As reported in the abstract
Adjusted risk (fold)
1.53
95% CI 1.11–2.11
P = 0.009
By group
Observational data: associations, not effects.
Further findings
All-cause readmission · 3 years · unadjusted P = 0.029
adjusted risk (fold) 1.52 (1.09–2.11) · P = 0.014
Readmission for non-HF · 3 years · unadjusted P = 0.004
adjusted risk (fold) 1.70 (1.21–2.38) · P = 0.002
| Outcome | Frail | Non-frail |
|---|---|---|
| Prevalence of frailty | 27.9% | — not stated in the abstract |
— not stated in the abstract
Original publication
Prevalence and Prognosis of Frailty in Older Patients with Stage B Heart Failure with Preserved Ejection Fraction. ESC Heart Fail. Published 4 January 2023. doi:10. 1002/ ehf2. 14274
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