Valvular & structural heart disease
Prevalence and prognostic impact of dynamic atrial functional mitral regurgitation assessed by isometric handgrip exercise
Authors' conclusion
Handgrip exercise during echocardiography revealed exercise-induced changes in aFMR in every third patient.
Study context
- Population
- Patients with atrial functional mitral regurgitation (MR) (at least mild MR) undergoing handgrip exercise echocardiography, University Hospital Duesseldorf, 2019–2021median age 80
- Participants
- 80 patients
- Exposure
- Severe MR at rest vs Exercise-induced dynamic severe MR vs Non-severe MR
- Severe MR at restn = 17
- Outcome
- Prevalence, extent and prognostic impact of exercise-induced changes in atrial functional mitral regurgitation (aFMR)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Exercise-induced changes in MR severity
Non-severe MR at rest becoming severe during exercise
17.5%
Reclassification of MR severity with handgrip exercise
28 patients
35.0%
Observational data: associations, not effects.
Further findings
Adverse events · 1-year follow-up
- Adverse events: P < 0.001
MR severity at rest
- Mild MR
- 53.8%
- Moderate MR
- 20 patients (25.0%)
- Severe MR
- 17 patients (21.2%)
Original publication
Prevalence and prognostic impact of dynamic atrial functional mitral regurgitation assessed by isometric handgrip exercise. Eur Heart J Cardiovasc Imaging. Published 8 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →