Prevalence and prognostic importance of chronic kidney disease in patients with coronary heart disease: results from the combined EUROASPIRE IV and V studies
Authors' conclusion
CKD is common among people with CHD and constitutes an independent risk factor for recurrent CVD events.
Study context
- Population
- Patients with established coronary heart disease (CHD)9,872 with follow-up
- Participants
- 10,349 patients
- Exposure
- Chronic kidney disease (CKD) risk categories
- Outcome
- Time to first CV death, non-fatal MI, stroke, HF hospitalization, bypass surgery or PCI
- Follow-up
- Median 1.6 years
Methodological detailscombined EUROASPIRE IV and V
- Combined EUROASPIRE IV and V
Main finding
As reported in the abstract
Primary endpoint
Each group vs low riskHazard ratio (95% CI)P value
Moderate risk
1.39(1.19–1.63)
P < 0.0001High risk
1.75(1.44–2.12)
P < 0001Observational data: associations, not effects.
Further findings
CKD prevalence (eGFR and urinary albumin/creatinine ratio (UACR))
- CKD
- 27.3%
- Low or moderate risk
- 18.2%
- High or very high risk
- 9.1%
- Not diagnosed without UACR
- 48.9%
Original publication
Prevalence and prognostic importance of chronic kidney disease in patients with coronary heart disease: results from the combined EUROASPIRE IV and V studies. Eur J Prev Cardiol. Published 29 August 2025. doi:10.
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