Recent COVID-19 and mortality after myocardial infarction: a Danish nationwide cohort study
Authors' conclusion
Recent COVID-19 was associated with increased short-term mortality after MI in patients without prior COVID-19 vaccination.
Study context
- Population
- Adults admitted with a first-time myocardial infarction (MI) to a Danish hospital, May 26, 2020, to March 9, 2022
- Participants
- 12,054 adults
- Exposure
- Recent COVID-19 vs no recent COVID-19 before MI
- Recent COVID-19n = 337
- Outcome
- All-cause mortality
- Follow-up
- 30 or 180 days after MI
Methodological detailsstabilized inverse probability weighting, Danish registries
- Stabilized inverse probability weighting
- Danish registries
Main finding
As reported in the abstract
Recent COVID-19 vs No recent COVID-19Adjusted hazard ratio (95% CI)
30-day mortality
1.64(1.16–2.31)
180-day mortality
1.28(0.92–1.78)
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted HR (95% CI) | |
|---|---|---|
| Mortality, unvaccinated (subgroup)Recent COVID-19vs No recent COVID-1930-day mortality | 2.88 (1.78–4.64) | |
| Mortality, unvaccinated (subgroup)Recent COVID-19vs No recent COVID-19180-day mortality | 2.09 (1.30–3.36) | |
| Mortality, vaccinated (subgroup)Recent COVID-19vs No recent COVID-1930-day mortality | 1.11 (0.65–1.90) | |
| Mortality, vaccinated (subgroup)Recent COVID-19vs No recent COVID-19180-day mortality | 0.97 (0.60–1.56) | |
| 0.20.5125Adjusted hazard ratio (log scale) |
Original publication
Recent COVID-19 and mortality after myocardial infarction: a Danish nationwide cohort study. Eur J Prev Cardiol. Published 28 August 2025. doi:10.
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