Arrhythmias & electrophysiology
Prevalence, timing, and impact of early recurrence of atrial tachyarrhythmias after pulsed field ablation: A secondary analysis of the PULSED atrial fibrillation (AF) trial
Authors' conclusion
ERAT after PFA predicted LRAT in patients with paroxysmal and persistent AF.
Study context
- Population
- Patients with AF undergoing pulsed field ablation (PFA) with ≥10 rhythm assessments during the 90-day blanking period
- Participants
- 154 vs 140
- Comparison
- Paroxysmal AF vs persistent AF after PFA
- Paroxysmal AFn = 154
- Persistent AFn = 140
- Primary endpoint
- Prevalence of ERAT (≥30 s of AF, atrial flutter or atrial tachycardia on transtelephonic monitoring, or ≥10 s on ECG at 3 months)
- Follow-up
- Within 90 days
Primary result
As reported in the abstract
ERAT prevalence · 90-day blanking period
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| LRAT (90 days–12 months), ERAT vs no ERATERATvs No ERATParoxysmal AF | 6.4 (3.6–11.3) | |
| LRAT (90 days–12 months), ERAT vs no ERATERATvs No ERATPersistent AF | 3.8 (2.2–6.6) | |
| 0.050.21520Hazard ratio (log scale) |
No LRAT among patients with ERAT
Early recurrence of atrial tachyarrhythmias (ERAT) onset within first month (patients with ERAT)
- ERAT onset within the first month
- 73%
Late recurrence of atrial tachyarrhythmias (LRAT) vs number of ERAT observations
- LRAT positively correlated with number of ERAT observations
Original publication
Prevalence, timing, and impact of early recurrence of atrial tachyarrhythmias after pulsed field ablation: A secondary analysis of the PULSED AF trial. Heart Rhythm. Published 24 June 2024. doi:10.
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