Arrhythmias & electrophysiology
Redefining the blanking period after pulsed field ablation in patients with atrial fibrillation
Authors' conclusion
In this consecutive series of patients with AF, early recurrence in the second or third month after the PFA procedure was associated with a high risk of late recurrence.
Study context
- Population
- Patients with AF undergoing pulsed-field ablation (PFA) with pulmonary vein isolation
- Participants
- 337 patients
- Exposure
- Early recurrence by month of blanking period after PFA
- Recurrence month 1n = 10
- Recurrence month 2n = 12
- Recurrence month 3n = 31
- Outcome
- Late recurrence (any recurrence beyond 3 months) after early recurrence (atrial arrhythmia >30 s during 3-month blanking period)
- Follow-up
- 1 year
Methodological detailsconsecutive patients, AADs continued during 2-month blanking period, then discontinued
- Consecutive patients
- AADs continued during 2-month blanking period, then discontinued
Main finding
As reported in the abstract
| Group | Value | Sinus rhythm after cardioversion | Redo procedure for late recurrence | Redo procedure (all had late recurrence) |
|---|---|---|---|---|
| Recurrence month 1 | 70% | 7 (70%) | 3 (30%) | |
| Recurrence month 2 | 83.3% | 10 (83.3%) of 12 | ||
| Recurrence month 3 | 87% | 27 (87%) of 31 |
Value
Recurrence month 170%
Recurrence month 283.3%
Recurrence month 387%
Sinus rhythm after cardioversion
Recurrence month 17 (70%)
Recurrence month 2— not stated in the abstract
Recurrence month 3— not stated in the abstract
Redo procedure for late recurrence
Recurrence month 13 (30%)
Recurrence month 2— not stated in the abstract
Recurrence month 3— not stated in the abstract
Redo procedure (all had late recurrence)
Recurrence month 1— not stated in the abstract
Recurrence month 210 (83.3%) of 12
Recurrence month 327 (87%) of 31
- Early recurrence overall
- 53 patients (15.7%)
Observational data: associations, not effects.
Original publication
Redefining the blanking period after pulsed field ablation in patients with atrial fibrillation. Heart Rhythm. Published 6 August 2024. doi:10.
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