Heart failure & cardiomyopathies
Preventive Catheter Ablation for Ventricular Arrhythmias in Patients with End-Stage Heart Failure Referred for Heart Transplantation Evaluation: Rationale for and Design of the CASTLE-VT Trial
Study context
- Population
- Patients with end-stage heart failure (HF) related to ischaemic cardiomyopathy referred for heart transplantation evaluationplanned
- Participants
- 160 patients
- Planned comparison
- Prophylactic substrate-based catheter ablation of ventricular scar vs no ablation
- Primary endpoint
- Composite of:
- All-cause mortality
- Worsening of HF requiring prioritized transplantation
- Left ventricular assist device (LVAD) implantation
Methodological detailsrationale and design
- Rationale and design
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Preventive Catheter Ablation for Ventricular Arrhythmias in Patients with End-Stage Heart Failure Referred for Heart Transplantation Evaluation: Rationale for and Design of the CASTLE-VT Trial. Eur J Heart Fail. Published 11 November 2024. doi:10.
Summarised from the published abstract; every number is checked against it