Heart failure & cardiomyopathies

Proactive Heart Failure Screening in Obesity: Design, Recruitment and Baseline Characteristics of the SCORHFE Trial

ESC Heart FailPublished trial

Study context

Population
Adults aged 45 years or older with obesity and no known cardiac diseaserandomised, 746 expressed interest, 629 (84.3%) underwent eligibility assessment
Participants
420 adults
Planned comparison
Proactive multimodal heart failure screening or usual care
Primary endpoint
left ventricular dysfunction and/or acute heart failure hospitalisation
Follow-up
1 year
Methodological detailsrandomised 1:1
  • Randomised 1:1

No results yet. This paper sets out the design of a trial; its results are to come.

Baseline

Baseline characteristics

Mean age
58.3 ± 8.4 years
Women
295 participants (70.2%)
Median body mass index
35.0 [32.4-38.0] kg/m²
Central obesity, among 385 participants with available waist circumference data
379 (98.4%)
Two or more cardiometabolic conditions
Ninety-seven participants (23.1%)

Screening acceptability, among a random subset of 50 screened participants

Considered screening duration acceptable, of the 50
46 (92.0%)
Reported low procedural burden, of the 50
47 (94.0%)
Supported routine implementation, of the 50
46 (92.0%)

Original publication

Proactive Heart Failure Screening in Obesity: Design, Recruitment and Baseline Characteristics of the SCORHFE Trial. ESC Heart Fail. Published 28 September 2026. doi:10.1093/eschf/xvag244

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