Valvular & structural heart disease
Procedural and Clinical Outcomes According to Ultrasound-Guided Access in Transcatheter Aortic Valve Implantation (TAVI): A Propensity-Matched Comparative Subanalysis From the PULSE Registry
Main finding · Composite of minor and major vascular complications or bleeding type II-IV (Valve Academic Research Consortium definitions)Result — go to the resultOdds ratio 0.7Authors' conclusion
In patients with transfemoral TAVI, USG access demonstrated lower rates of access-related vascular complications and type II-IV bleeding compared with fluoroscopy-guided access. Implementing USG puncture as the standard of care may improve access-related outcomes after TAVI.
Study context
- Population
- Patients who underwent transfemoral TAVI at German heart centers (2016–2021)895 matched pairs after propensity score matching
- Participants
- 9,295 patients
- Exposure
- Ultrasound-guided (USG) versus fluoroscopy-guided access
- USGn = 1,992 (21.4%)
- Fluoroscopy-guidedn = 7,303 (78.6%)
- Outcome
- Composite of minor and major vascular complications or bleeding type II-IV (Valve Academic Research Consortium definitions)
Methodological detailsretrospectively evaluated, 10 high-volume German heart centers, Propensity score matching (1:1)
- Retrospectively evaluated
- 10 high-volume German heart centers
- Propensity score matching (1:1)
Main finding
As reported in the abstract
Odds ratio
0.7
P = 0.01
By group
Observational data: associations, not effects.
Further findings
Procedural bleeding
odds ratio 0.56 · P = 0.002
Endovascular treatment
Median EuroSCORE II
| Outcome | USG | Fluoroscopy-guided |
|---|---|---|
| Baseline characteristics | 3.2 | 3.5 |
- Baseline characteristics — median age
- 81.9 [78.3-85.0] years
- Baseline characteristics — female patients
- 47.8%
- Baseline characteristics — SD
- 0.007 [−0.086 to 0.099]
- Endovascular treatment: P =0.005
Baseline characteristics
- Well-balanced baseline characteristics
Original publication
Procedural and Clinical Outcomes According to Ultrasound-Guided Access in TAVI: A Propensity-Matched Comparative Subanalysis From the PULSE Registry. Circ Cardiovasc Interv. Published 29 May 2025. doi:10. 1161/ circinterventions. 124. 014771
Composed by AI from the published abstract and checked against it. How Briefs are made →