Valvular & structural heart disease

Procedural and Clinical Outcomes According to Ultrasound-Guided Access in Transcatheter Aortic Valve Implantation (TAVI): A Propensity-Matched Comparative Subanalysis From the PULSE Registry

Circ Cardiovasc IntervPublished Propensity-Matched Comparative Subanalysis From the PULSE Registry

Main finding · Composite of minor and major vascular complications or bleeding type II-IV (Valve Academic Research Consortium definitions)Result — go to the resultOdds ratio 0.7

Authors' conclusion

In patients with transfemoral TAVI, USG access demonstrated lower rates of access-related vascular complications and type II-IV bleeding compared with fluoroscopy-guided access. Implementing USG puncture as the standard of care may improve access-related outcomes after TAVI.

Study context

Population
Patients who underwent transfemoral TAVI at German heart centers (2016–2021)895 matched pairs after propensity score matching
Participants
9,295 patients
Exposure
Ultrasound-guided (USG) versus fluoroscopy-guided access
  • USGn = 1,992 (21.4%)
  • Fluoroscopy-guidedn = 7,303 (78.6%)
Outcome
Composite of minor and major vascular complications or bleeding type II-IV (Valve Academic Research Consortium definitions)
Methodological detailsretrospectively evaluated, 10 high-volume German heart centers, Propensity score matching (1:1)
  • Retrospectively evaluated
  • 10 high-volume German heart centers
  • Propensity score matching (1:1)

Main finding

As reported in the abstract

Odds ratio

0.7

P = 0.01

By group

Observational data: associations, not effects.

Further findings

Procedural bleeding

odds ratio 0.56 · P = 0.002

Endovascular treatment

Median EuroSCORE II

OutcomeUSGFluoroscopy-guided
Baseline characteristics3.23.5
Baseline characteristics — median age
81.9 [78.3-85.0] years
Baseline characteristics — female patients
47.8%
Baseline characteristics — SD
0.007 [−0.086 to 0.099]
  • Endovascular treatment: P =0.005

Baseline characteristics

Well-balanced baseline characteristics

Original publication

Procedural and Clinical Outcomes According to Ultrasound-Guided Access in TAVI: A Propensity-Matched Comparative Subanalysis From the PULSE Registry. Circ Cardiovasc Interv. Published 29 May 2025. doi:10.1161/circinterventions.124.014771

Composed by AI from the published abstract and checked against it. How Briefs are made →

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