Valvular & structural heart disease
Femoral or Radial Secondary Access in Transcatheter Aortic Valve Replacement (TAVR): A Subanalysis From the Multicenter PULSE Registry
Authors' conclusion
During transfemoral TAVR, TR-SA was associated with lower rates of access site complications and severe bleeding compared to TF-SA.
Study context
- Population
- Patients undergoing transfemoral TAVR at 10 heart centres, 2016–2021 (PULSE registry)of 10,120 in registry
- Participants
- 8,851 patients
- Exposure
- Transradial vs transfemoral secondary access for pigtail placement in TAVR
- Transradial secondary access (TR-SA)n = 1,686
- Traditional femoral secondary access (TF-SA)n = 7,165reference
- Outcome
- Secondary access-related vascular complications (VARC-3)
Methodological detailsregistry, multicentre, propensity-score matched
- Registry
- Multicentre
- Propensity-score matched
Main finding
As reported in the abstract
Secondary access vascular complications
P < 0.001
Observational data: associations, not effects.
Further findings
Major secondary access vascular complications
P < 0.001
Minor secondary access vascular complications
P < 0.001
Secondary access vascular complications, propensity-matched
P < 0.001
- Secondary access vascular complications, propensity-matched: matched cohort (1:1, 512 per group)
Safety
Primary access vascular complications
P = 0.93
Bleeding type III/IV
P < 0.001
| Outcome | TR-SA | TF-SA |
|---|---|---|
| Surgical repair required | 0 events | 0.9% |
Original publication
Femoral or Radial Secondary Access in TAVR: A Subanalysis From the Multicenter PULSE Registry. JACC Cardiovasc Interv. Published 23 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →