Heart failure & cardiomyopathies
Prognosis and predictors of right ventricular dysfunction by quantitative cardiac magnetic resonance in non-ischaemic cardiomyopathy
Main finding · Primary endpoint per 5% increase in RVEFResult — go to the resultHazard ratio 0.80 95% CI 0.73–0.88Authors' conclusion
RVEF provides powerful risk stratification, with RVEF ≤ 40% defining significant RV dysfunction associated with adverse outcomes in NICM.
Study context
- Population
- Non-ischaemic cardiomyopathy (NICM) patients undergoing CMR, 2002–2017
- Participants
- 624 patients
- Outcome
- All-cause mortality, heart transplant and/or LV assist device implantation
Main finding
Primary endpoint per 5% increase in RVEF
Hazard ratio
0.80
95% CI 0.73–0.88
P < 0.001
RVEF per 5% increase
HR 0.80 (95% CI 0.73–0.88); P < 0.001
Per 5% increase, as printed
As reported in the abstract
- Mean right ventricular ejection fraction (RVEF)
- 43 ± 13%
Observational data: associations, not effects.
Further findings
Factors associated with reduced RVEF
- Male sex, New York Heart Association (NYHA) III-IV, right bundle branch block, lower LVEF, higher mitral regurgitant fraction (MR-RF) and right ventricle (RV) size
Late gadolinium enhancement (LGE) and MR-RF and primary endpoint
- Higher LGE associated with primary endpoint only in RVEF ≤ 40%
- Risk associated with MR-RF significantly dampened after adjusting for RVEF
Original publication
Prognosis and predictors of right ventricular dysfunction by quantitative cardiac magnetic resonance in non-ischaemic cardiomyopathy. Eur Heart J Cardiovasc Imaging. Published 17 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →