Acute cardiac care & resuscitation
Prognosis of Cardiogenic Shock Secondary to Culprit Left Main Coronary Artery Lesion-Related Myocardial Infarction
Authors' conclusion
ULMCA-related AMICS was associated with a high in-hospital mortality or need for HT or LVAD. Prognosis was especially poor among patients with profound shock and baseline occluded LMCA, with a low probability of recovery regardless of successful PCI.
Study context
- Population
- Patients with cardiogenic shock secondary to unprotected left main coronary artery-related MI (ULMCA-related AMICS), 2012–20
- Participants
- 70 patients
- Outcome
- Death or requirement for heart transplantation (HT) or LVAD
- Follow-up
- During the admission
Methodological detailstwo tertiary care centres
- Two tertiary care centres
Main finding
As reported in the abstract
Death or heart transplantation (HT) or left ventricular assist devices (LVAD), whole cohort
41 of 70
58.6%
Observational data: associations, not effects.
Further findings
Primary endpoint by PCI success, whole cohort
P = 0.026
Primary endpoint by PCI success, profound shock and occluded LMCA (subgroup)
P = 0.731
Primary endpoint in profound shock and occluded left main coronary artery (LMCA) (subgroup)
- Highest incidence of the primary endpoint
- 20/23, 87%, P < 0.001
Predictive model (LVEF, baseline ULMCA TIMI flow, shock severity) for death or HT or LVAD
- AUC
- 0.865, P < 0.001
Successful percutaneous coronary intervention (PCI)
- PCI successful
- 53/70 (75.7%)
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →