Acute cardiac care & resuscitation
Percutaneous Coronary Intervention in Multivessel Disease and Infarct-Related Cardiogenic Shock: A DanGer Shock Substudy
Primary result · All-cause mortalityResult — go to the resultAdjusted odds ratio 0.40 95% CI 0.19–0.83Authors' conclusion
Immediate multivessel PCI was associated with 60% lower odds of all-cause mortality compared with culprit-only PCI.
Study context
- Population
- STEMI-related cardiogenic shock with multivessel disease (≥1 nonculprit stenosis ≥70%), excluding comatose patients resuscitated from cardiac arrest and isolated left main culpritof 355 in DanGer Shock
- Participants
- 221 participants
- Comparison
- Immediate multivessel percutaneous coronary intervention (PCI) vs culprit-only PCI
- Immediate multivessel PCIn = 103
- Culprit-only PCIn = 118reference
- Primary endpoint
- All-cause mortality
- Follow-up
- 180 days
Methodological detailsexploratory substudy, multicentre, as-treated analysis
- Exploratory substudy
- Multicentre
- As-treated analysis
Primary result
As reported in the abstract
median follow-up 45 days (Q1-Q3: 2-180 days)
Adjusted odds ratio
0.40
95% CI 0.19–0.83
Events by treatment group
Immediate multivessel PCIvs Culprit-only PCI
adjusted OR 0.40 (95% CI 0.19–0.83)
Secondary outcomes
Renal replacement therapy and acute kidney injury
- Immediate multivessel PCI not associated with the secondary outcomes
Original publication
Percutaneous Coronary Intervention in Multivessel Disease and Infarct-Related Cardiogenic Shock: A DanGer Shock Substudy. JACC Cardiovasc Interv. Published 22 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →